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Nutrition and Canine Cancer: A Powerful Ally

Mariette du Plessis | Feb 12, 2025
Role of Antioxidants in Dog Health
Diet and Nutrition
When a beloved dog faces the daunting diagnosis of cancer, every pet owner seeks hope and solutions. One of the most overlooked ways to support our canine companions is through nutrition. In this post, we delve into dietary choices and what the evidence says about their role in supporting dogs with cancer.
When a beloved dog faces the daunting diagnosis of cancer, every pet owner seeks hope and solutions. One of the most overlooked ways to support our canine companions is through nutrition. In this post, we delve into dietary choices and what the evidence says about their role in supporting dogs with cancer.
 

Understanding the Enemy: The Science Behind Cancer Growth

First, let's grasp the science behind cancer's relentless growth. Neoplastic cells, the culprits behind cancer, rely heavily on glucose to fuel their rapid division. They take up far more glucose than normal cells and convert much of it to lactate, even when oxygen is available. Scientists call this the Warburg effect, and its exact role in tumour growth is still unclear.

Research also indicates that dogs with cancer have changes in the way their bodies handle carbohydrates, and keeping up body weight and muscle becomes a real priority. But there's hope.
 

Diet and Cancer: High-Fat, High-Protein, Low-Carb?

Because cancer cells readily use glucose, one proposed strategy is a dietary shift that prioritises fats and proteins over carbohydrates. The theory is reasonable, but it has not been proven. Lower-carbohydrate diets have not yet been shown to improve survival or remission in dogs with cancer, and in non-diabetic dogs the body keeps blood sugar within a narrow range whatever the diet.

There is no single ideal cancer diet for dogs, and no set percentage of protein or fat has been shown to slow the disease. The main goals are to meet your dog's calorie needs with a complete and balanced diet and to maintain body weight and muscle. Not every dog tolerates a high-fat diet, and other medical conditions can rule out high-fat or high-protein feeding, so speak with your vet or veterinary oncologist before changing the diet.
 

Amino Acids: The Building Blocks of Hope

Certain amino acids have been studied for a possible role in cancer care. Arginine is one example. It was included, together with omega-3 fatty acids, in a diet tested in small clinical trials in dogs with cancer, but studies of arginine in people with cancer have been conflicting, with some showing benefit and others harm. Glutamine, found in foods like meat, milk, cheese, and spinach, has also attracted interest, but there is no strong evidence that adding it slows cancer in dogs.

Branched-chain amino acids such as leucine play a part in muscle protein metabolism, and maintaining lean mass matters for dogs with cancer. Even so, amino acid supplements have not been shown to prevent muscle wasting or slow cancer in dogs. The priority is a complete and balanced diet with enough calories and protein, so ask your vet before adding any supplement.
 

Omega-3 Fatty Acids: A Ray of Hope

Omega-3 fatty acids have shown some potential anti-cancer effects in cell and rodent studies. Small clinical trials of a diet high in omega-3 fatty acids and arginine also reported some positive effects, including longer survival times in some dogs with lymphoma. EPA and DHA, commonly found in fish oils, may be helpful for dogs with cancer, but there have not been many studies in dogs and the best dose has not been established, so ask your vet before adding fish oil.
 

Antioxidants and Minerals: A Word of Caution

Common antioxidants such as beta-carotene, retinoids, and vitamins C and E have prevented the kind of cell damage linked to cancer in laboratory and animal studies. Large clinical trials in people, however, have not shown that antioxidant supplements prevent cancer, and some found harm. High-dose antioxidant supplements may also work against chemotherapy or radiotherapy. Selenium is a trace mineral that dogs need only in tiny amounts, and too much is toxic. Never give selenium or any other antioxidant supplement to a dog with cancer unless your vet has recommended it and set the amount.

In conclusion, when it comes to your dog's battle against cancer, nutrition is a powerful ally. By understanding the role of diet and making informed choices, we can provide hope and support in the fight against this relentless disease. Remember, every bite counts in the journey to better health and a brighter future for our canine companions.
 

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